ADx-ARMS^® technology enables the detection of gene mutations by designing a specific primer at the mutation site. This technology leverages the capability of DNA polymerase to differentiate between a matched and a mismatched base at the 3’ end of a PCR primer.

In cases where the 3’ base of the primer perfectly matches the mutant template, amplification proceeds efficiently. Conversely, when the 3’ base mismatches with the wild-type template, amplification efficiency is significantly reduced.
This selective amplification allows for the detection of specific mutated sequences even in samples where the majority of DNA lacks the mutation.

Super-ARMS^® represents an advancement over traditional ARMS technology achieved through enhanced primer and probe design.
With Super-ARMS, efficient amplification occurs when the 3’ base of the primer perfectly matches the mutant template. Conversely, if the 3’ base mismatches with the wild-type template, amplification efficiency is significantly reduced.

The refined primer design significantly enhances both specificity and sensitivity, offering improved performance in mutation detection.

AmoyDx^® Automated Result Analysis System (ARAS), an advanced software designed to automate the interpretation of AmoyDx PCR data, elevating your laboratory workflow to new heights. ARAS is crafted to streamline PCR data analysis, delivering timely and comprehensive results with a focus on precision and efficiency.

Explore our online educational web-based ARAS software at http://support.amoydx.com/, designed for training, evaluation, and troubleshooting.