The Super-ARMS® EGFR Mutation Detection Kit is a real-time PCR assay. This kit facilitates the qualitative detection of up to 31 somatic mutations in exons 18-21 of the EGFR gene using human circulating DNA extracted from plasma/serum. It is intended to assist in identifying EGFR mutation status in patients with non-small cell lung cancer (NSCLC) who may qualify for approved targeted therapies. The kit is for in vitro diagnostic use and is intended for use by trained professionals in a laboratory setting.
Specifications
Tests/kit
12 (Bulk)
Instrument
Stratagene Mx3000P™, ABI 7300, ABI 7500, ABI 7900HT, ABI StepOnePlus, LightCycler480 II, cobas® z480, Bio-Rad CFX96, SLAN-96S
Shelf-life
8 months
Publications
1. Wu, W., Huang, Y., Guo, J., Xie, X., Li, H., Cao, Z., Wei, H. and Wu, C. (2020), Detection and comparison of EGFR mutations from supernatants that contain cell-free DNA and cell pellets from FNA non–small cell lung cancer specimens. Cancer Cytopathology, 128: 545-552.
2. Wu, W., Cao, Z., Zhang, W. et al. Comparison of the SuperARMS and ARMS for detecting EGFR mutations in liquid-based cytology specimens from NSCLC patients. Diagn Pathol 15, 9 (2020).
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