The AmoyDx® OncoPro Liquid NGS Panel is a next-generation sequencing (NGS)-based assay designed for the qualitative detection of single nucleotide variants (SNVs), insertions and deletions (InDels), gene fusions, and copy number variations (CNVs) across 152 target genes, as well as for determining tumor microsatellite instability (MSI) status. The panel detects these genetic alterations using circulating cell-free DNA (cfDNA) extracted from plasma, derived from anticoagulated peripheral whole blood samples.
Mutations( Hover over each mutational type to highlight genes covered )
All
ABRAXAS1
ABRAXAS1
SNV/INDELS
AKT1
AKT1
SNV/INDELS
AKT2
AKT2
SNV/INDELS
AKT3
AKT3
SNV/INDELS
ALK
ALK
FUSIONS
SNV/INDELS
APC
APC
SNV/INDELS
AR
AR
FUSIONS
SNV/INDELS
ARAF
ARAF
SNV/INDELS
ARID1A
ARID1A
SNV/INDELS
ATM
ATM
SNV/INDELS
ATR
ATR
SNV/INDELS
AURKA
AURKA
SNV/INDELS
B2M
B2M
SNV/INDELS
BAP1
BAP1
SNV/INDELS
BARD1
BARD1
SNV/INDELS
BCL2L11
BCL2L11
SNV/INDELS
BRAF
BRAF
FUSIONS
SNV/INDELS
BRCA1
BRCA1
CNV
SNV/INDELS
BRCA2
BRCA2
CNV
SNV/INDELS
BRIP1
BRIP1
SNV/INDELS
CCND1
CCND1
SNV/INDELS
CCND2
CCND2
SNV/INDELS
CCNE1
CCNE1
SNV/INDELS
CD274
CD274
SNV/INDELS
CDH1
CDH1
SNV/INDELS
CDK12
CDK12
SNV/INDELS
CDK4
CDK4
SNV/INDELS
CDK6
CDK6
SNV/INDELS
CDKN2A
CDKN2A
SNV/INDELS
CDKN2B
CDKN2B
SNV/INDELS
CHEK1
CHEK1
SNV/INDELS
CHEK2
CHEK2
SNV/INDELS
CTNNB1
CTNNB1
SNV/INDELS
CYP2D6
CYP2D6
SNV/INDELS
DDR2
DDR2
SNV/INDELS
DPYD
DPYD
SNV/INDELS
EGFR
EGFR
FUSIONS
SNV/INDELS
EPCAM
EPCAM
SNV/INDELS
ERBB2
ERBB2
CNV
FUSIONS
SNV/INDELS
ERBB3
ERBB3
SNV/INDELS
ERBB4
ERBB4
FUSIONS
SNV/INDELS
ERCC1
ERCC1
SNV/INDELS
ERCC2
ERCC2
SNV/INDELS
ERCC3
ERCC3
SNV/INDELS
ERCC4
ERCC4
SNV/INDELS
ESR1
ESR1
FUSIONS
SNV/INDELS
EZH2
EZH2
SNV/INDELS
FANCA
FANCA
SNV/INDELS
FANCD2
FANCD2
SNV/INDELS
FANCL
FANCL
SNV/INDELS
FANCM
FANCM
SNV/INDELS
FBXW7
FBXW7
SNV/INDELS
FGF19
FGF19
SNV/INDELS
FGF3
FGF3
SNV/INDELS
FGFR1
FGFR1
FUSIONS
SNV/INDELS
FGFR2
FGFR2
FUSIONS
SNV/INDELS
FGFR3
FGFR3
FUSIONS
SNV/INDELS
FGFR4
FGFR4
FUSIONS
SNV/INDELS
FH
FH
SNV/INDELS
GATA3
GATA3
SNV/INDELS
GEN1
GEN1
SNV/INDELS
GNA11
GNA11
SNV/INDELS
GNAQ
GNAQ
SNV/INDELS
GNAS
GNAS
SNV/INDELS
HDAC2
HDAC2
SNV/INDELS
HNF1A
HNF1A
SNV/INDELS
HRAS
HRAS
SNV/INDELS
IDH1
IDH1
SNV/INDELS
IDH2
IDH2
SNV/INDELS
JAK1
JAK1
SNV/INDELS
JAK2
JAK2
SNV/INDELS
JAK3
JAK3
SNV/INDELS
KDR
KDR
SNV/INDELS
KEAP1
KEAP1
SNV/INDELS
KIT
KIT
FUSIONS
SNV/INDELS
KRAS
KRAS
SNV/INDELS
MAP2K1
MAP2K1
SNV/INDELS
MAP2K2
MAP2K2
SNV/INDELS
MAP2K4
MAP2K4
SNV/INDELS
MAPK1
MAPK1
SNV/INDELS
MAPK3
MAPK3
SNV/INDELS
MDM2
MDM2
SNV/INDELS
MDM4
MDM4
SNV/INDELS
MET
MET
CNV
FUSIONS
SNV/INDELS
MLH1
MLH1
SNV/INDELS
MPL
MPL
SNV/INDELS
MRE11
MRE11
SNV/INDELS
MSH2
MSH2
SNV/INDELS
MSH6
MSH6
SNV/INDELS
MTAP
MTAP
SNV/INDELS
MTOR
MTOR
SNV/INDELS
MUTYH
MUTYH
SNV/INDELS
MYC
MYC
SNV/INDELS
MYCN
MYCN
SNV/INDELS
NBN
NBN
SNV/INDELS
NF1
NF1
SNV/INDELS
NF2
NF2
SNV/INDELS
NFE2L2
NFE2L2
SNV/INDELS
NOTCH1
NOTCH1
SNV/INDELS
NPM1
NPM1
SNV/INDELS
NRAS
NRAS
SNV/INDELS
NRG1
NRG1
FUSIONS
SNV/INDELS
NTRK1
NTRK1
FUSIONS
SNV/INDELS
NTRK2
NTRK2
FUSIONS
SNV/INDELS
NTRK3
NTRK3
FUSIONS
SNV/INDELS
PALB2
PALB2
SNV/INDELS
PDCD1
PDCD1
SNV/INDELS
PDGFRA
PDGFRA
FUSIONS
SNV/INDELS
PIK3CA
PIK3CA
CNV
SNV/INDELS
PIK3CB
PIK3CB
SNV/INDELS
PIK3R1
PIK3R1
SNV/INDELS
PMS2
PMS2
SNV/INDELS
POLD1
POLD1
SNV/INDELS
POLE
POLE
SNV/INDELS
PPARG
PPARG
SNV/INDELS
PTCH1
PTCH1
SNV/INDELS
PTEN
PTEN
CNV
SNV/INDELS
PTPN11
PTPN11
SNV/INDELS
RAD50
RAD50
SNV/INDELS
RAD51
RAD51
SNV/INDELS
RAD51B
RAD51B
SNV/INDELS
RAD51C
RAD51C
SNV/INDELS
RAD51D
RAD51D
SNV/INDELS
RAD52
RAD52
SNV/INDELS
RAD54L
RAD54L
SNV/INDELS
RAF1
RAF1
FUSIONS
SNV/INDELS
RASA1
RASA1
SNV/INDELS
RB1
RB1
SNV/INDELS
RET
RET
FUSIONS
SNV/INDELS
RHEB
RHEB
SNV/INDELS
RHOA
RHOA
SNV/INDELS
RICTOR
RICTOR
SNV/INDELS
RIT1
RIT1
SNV/INDELS
RNF43
RNF43
SNV/INDELS
ROS1
ROS1
FUSIONS
SNV/INDELS
SETD2
SETD2
SNV/INDELS
SF3B1
SF3B1
SNV/INDELS
SLX4
SLX4
SNV/INDELS
SMAD4
SMAD4
SNV/INDELS
SMARCA4
SMARCA4
SNV/INDELS
SMO
SMO
SNV/INDELS
STK11
STK11
SNV/INDELS
TERT
TERT
FUSIONS
SNV/INDELS
TMPRSS2
TMPRSS2
FUSIONS
SNV/INDELS
TP53
TP53
SNV/INDELS
TSC1
TSC1
SNV/INDELS
TSC2
TSC2
SNV/INDELS
TSHR
TSHR
SNV/INDELS
UGT1A1
UGT1A1
SNV/INDELS
VHL
VHL
SNV/INDELS
XRCC1
XRCC1
SNV/INDELS
XRCC2
XRCC2
SNV/INDELS
Specifications
Sample Type
Plasma ctDNA
Tests/kit
24 reactions/kit
Target Regions
152 genes plus MSI
Instrument
Illumina NextSeq 500/550/550Dx (RUO), NovaSeq 6000
Inquiry