The AmoyDx® Myeloid Blood Cancer Panel employs next-generation sequencing (NGS) technology to qualitatively detect and identify single nucleotide variants (SNVs), insertions and deletions (InDels), and gene fusions within 55 genes associated with myeloid leukemia. This assay utilizes DNA and RNA extracted from bone marrow aspirate specimens obtained from patients diagnosed with acute myeloid leukemia or chronic myeloid leukemia.
Single Assay Solution for Detecting Variants Associated with Acute Myeloid Leukemia (AML) and Chronic Myeloid Leukemia (CML) Using Both DNA & RNA
Mutations( Hover over each mutational type to highlight genes covered )
All
ABL1
ABL1
FUSIONS
SNV/INDELS
ASXL1
ASXL1
SNV/INDELS
BCOR
BCOR
SNV/INDELS
BRAF
BRAF
SNV/INDELS
CALR
CALR
SNV/INDELS
CBFB
CBFB
FUSIONS
SNV/INDELS
CBL
CBL
SNV/INDELS
CEBPA
CEBPA
SNV/INDELS
CREBBP
CREBBP
FUSIONS
SNV/INDELS
CSF3R
CSF3R
SNV/INDELS
CTCF
CTCF
SNV/INDELS
DIS3
DIS3
SNV/INDELS
DNMT3A
DNMT3A
SNV/INDELS
ETV6
ETV6
FUSIONS
SNV/INDELS
EZH2
EZH2
SNV/INDELS
FBXW7
FBXW7
SNV/INDELS
FLT3
FLT3
SNV/INDELS
GATA1
GATA1
SNV/INDELS
GATA2
GATA2
SNV/INDELS
IDH1
IDH1
SNV/INDELS
IDH2
IDH2
SNV/INDELS
IKZF1
IKZF1
SNV/INDELS
JAK2
JAK2
FUSIONS
SNV/INDELS
JAK3
JAK3
SNV/INDELS
KIT
KIT
SNV/INDELS
KMT2A
KMT2A
FUSIONS
SNV/INDELS
KRAS
KRAS
SNV/INDELS
MAX
MAX
SNV/INDELS
MPL
MPL
SNV/INDELS
MYC
MYC
SNV/INDELS
MYD88
MYD88
SNV/INDELS
MLLT10
MLLT10
FUSIONS
NF1
NF1
SNV/INDELS
NPM1
NPM1
FUSIONS
SNV/INDELS
NRAS
NRAS
SNV/INDELS
NUP98
NUP98
FUSIONS
SNV/INDELS
NUP214
NUP214
FUSIONS
PDGFRA
PDGFRA
FUSIONS
SNV/INDELS
PHF6
PHF6
SNV/INDELS
PTPN11
PTPN11
SNV/INDELS
RB1
RB1
SNV/INDELS
RIT1
RIT1
SNV/INDELS
RUNX1
RUNX1
FUSIONS
SNV/INDELS
RARA
RARA
FUSIONS
SETBP1
SETBP1
SNV/INDELS
SF3B1
SF3B1
SNV/INDELS
SRSF2
SRSF2
SNV/INDELS
STAG2
STAG2
SNV/INDELS
STIL
STIL
FUSIONS
TET2
TET2
SNV/INDELS
TP53
TP53
SNV/INDELS
TCF3
TCF3
FUSIONS
U2AF1
U2AF1
SNV/INDELS
WT1
WT1
SNV/INDELS
ZRSR2
ZRSR2
SNV/INDELS
Specifications
Sample type
Bone Marrow
Alterations detected
SNV、Indel、Fusion
Sequencer
NovaSeq 6000, NextSeq 500/550, MiSeq, MiSeqDx
TAT from sample to report
3 days
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