AmoyDx® KNBM PCR Panel
PCR
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The AmoyDx ® KNBM PCR Panel is a qualitative real-time PCR assay designed to detect 34 somatic mutations in KRAS gene (exons 12, 13, 59, 61, 117, and 146), 24 somatic mutations in NRAS gene (exons 12, 13, 59, 61, and 146), the BRAF V600E mutation and microsatellite instability (MSI) in formalin-fixed paraffin-embedded (FFPE) tissue samples from colorectal cancer patients. The kit is capable of genotyping specific mutations, including BRAF p.V600E, KRAS p.G12A/C/D/R/S/V, and KRAS p.G13D.
This kit is intended for research use only and must be operated by trained professionals in a controlled laboratory environment. The kit is compatible with the LightCycler480 II, cobas z 480 and SLAN-96S platforms for testing and data collection. Results should be analyzed by ARAS, a specialized tool designed to assist in the interpretation of the AmoyDx ® KNBM PCR Panel results.
Comprehensive Clinical Utility - Empowering Precision CRC Management
Results in 6 hours with robust quality controls.
Includes 58 SNVs across KRAS/NRAS/BRAF and MSI analysis, with >99% coverage.
Detects mutations as low as 1% variant allele frequency (VAF).
Optimized KRAS Genotyping
Kit Format
12 tests / kit
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