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The AmoyDx® HANDLE Melanoma NGS Panel is an advanced next-generation sequencing (NGS) assay designed to qualitatively detect single nucleotide variants (SNVs), insertions and deletions (InDels) within pivotal melanoma tumor genes, utilizing DNA extracted from FFPE tumor tissue specimens.






 

Mutations( Hover over each mutational type to highlight genes covered )

All
SNV
SNV/INDELS
BRAF

BRAF

SNV/INDELS
CTNNB1

CTNNB1

SNV/INDELS
GNA11

GNA11

SNV/INDELS
GNAQ

GNAQ

SNV/INDELS
HRAS

HRAS

SNV/INDELS
KIT

KIT

SNV/INDELS
KRAS

KRAS

SNV/INDELS
NRAS

NRAS

SNV/INDELS
TERT

TERT

SNV

Comprehensive analysis of 9 key genes

Comprehensive analysis of 9 key genes

Superior Detection Rate

Superior Detection Rate

Short turnaround time within 3 days

Short turnaround time
within 3 days

Cost-effective & Broad Compatibility

Cost-effective & Broad Compatibility

Specifications

Sample type
FFPE tissue
Alterations Detected
SNV, InDel
DNA input
30-100 ng (50 ng is recommended)
Data output per sample
25 Mb/sample, (0.025 GB)
Sequencer
Illumina NextSeq 500/550, MiSeq/MiSeqDx, iSeq 100 (PE150)
TAT for library preparationn
5 hours (hands-on time 1 hour)
TAT from sample to report
3 days

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