The AmoyDx® HANDLE Melanoma NGS Panel is an advanced next-generation sequencing (NGS) assay designed to qualitatively detect single nucleotide variants (SNVs), insertions and deletions (InDels) within pivotal melanoma tumor genes, utilizing DNA extracted from FFPE tumor tissue specimens.
Mutations( Hover over each mutational type to highlight genes covered )
All
BRAF
BRAF
SNV/INDELS
CTNNB1
CTNNB1
SNV/INDELS
GNA11
GNA11
SNV/INDELS
GNAQ
GNAQ
SNV/INDELS
HRAS
HRAS
SNV/INDELS
KIT
KIT
SNV/INDELS
KRAS
KRAS
SNV/INDELS
NRAS
NRAS
SNV/INDELS
TERT
TERT
SNV
Specifications
Sample type
FFPE tissue
Alterations Detected
SNV, InDel
DNA input
30-100 ng (50 ng is recommended)
Data output per sample
25 Mb/sample, (0.025 GB)
Sequencer
Illumina NextSeq 500/550, MiSeq/MiSeqDx, iSeq 100 (PE150)
TAT for library preparationn
5 hours (hands-on time 1 hour)
TAT from sample to report
3 days
Inquiry