AmoyDx® HANDLE Breast Cancer NGS Panel
NGS
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The AmoyDx® Handle Breast Cancer NGS Panel is a highly sensitive assay that detects actionable mutations in key genes (PIK3CA, AKT1, PTEN, ESR1, ERBB2) across 241 hotspots. With a limit of detection (LOD) down to 0.2% variant allele frequency (VAF), it enables advanced research in HR+/HER2- breast cancer biology using both liquid biopsy and FFPE tissue samples.
Mutations( Hover over each mutational type to highlight genes covered )
All
AKT1
AKT1
SNV/INDELS
ERBB2
ERBB2
SNV/INDELS
ESR1
ESR1
SNV/INDELS
PTEN
PTEN
SNV/INDELS
PIK3CA
PIK3CA
SNV/INDELS
Highly Sensitive with LOD as low as 0.2% VAF from plasma cfDNA
Fast turnaround time in 4 days
Optimized HANDLE Workflow
Cost- effective
Specifications
Sample Type
plasma cfDNA, FFPE tissue
Alterations Detected
SNV, InDel
Kit format
24 tests/kit
Sequencers
Illumina NextSeq 500/550, Salus Pro
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