AmoyDx® BRCA Pro Panel
White Paper
1. Comparative Analysis of BRCA Pro Data on MGI DNBSEQ-G50 and NextSeq 550
The study confirms that the AmoyDx® BRCA Pro Panel performs exceptionally well on both MGI G50 and NextSeq 550 platforms. The MGI G50 demonstrated superior sequencing quality and depth while maintaining comparable accuracy, mutation frequency detection, and detection performance. These findings validate MGI G50 as a robust and reliable platform for BRCA mutation screening in both clinical and research applications.Mutations( Hover over each mutational type to highlight genes covered )
BRCA1
BRCA2
Detection of SNVs,
InDels and LRs
Decentralized kit solution with ease of use
Fast turnaround time
and cost-effective
Streamlined one-tube workflow
Specifications
Publications
1. Dong, Z., Wang, Y., Zhang, J. et al. Analyzing the effects of BRCA1/2 variants on mRNA splicing by minigene assay. J Hum Genet 68, 65–71 (2023).
2. Zhang, R., Gao, P., Han, Y. et al. Reliable assessment of BRCA1 and BRCA2 germline variants by next-generation sequencing: a multicenter study. Breast Cancer 28, 672–683 (2021).